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1

Backbone assignments and secondary structure of the Escherichia coli enzyme-II mannitol a domain determined by heteronuclear three-dimensional NMR spectroscopy

Gerard J. A. Kroon, Klaas Dijkstra, Ruud M. Scheek, George T. Robillard, Joachim Grötzinger

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 2.12 MB

english, 1993

2

Functional characterization of three CYP21A2 sequence variants (p.A265V, p.W302S, p.D322G) employing a yeast co-expression system

Caroline Bleicken, Lourdes Loidi, Vivek Dhir, Silvia Parajes, Celsa Quinteiro, Fernando Dominguez, Joachim Grötzinger, Wolfgang G. Sippell, Felix G. Riepe, Wiebke Arlt, Nils Krone

Journal:

Year:

2009

Language:

english

File:

PDF, 658 KB

english, 2009

3

Carbonate deposition and hydrocarbon reservoir development at the Precambrian–Cambrian boundary: The Ara Group in South Oman

Stefan Schröder, John P. Grotzinger, Joachim E. Amthor, Albert Matter

Journal:

Sedimentary Geology

Year:

2005

Language:

english

File:

PDF, 1001 KB

english, 2005

4

The IL-6/sIL-6R complex as a novel target for therapeutic approaches

Rose-John, Stefan, Waetzig, Georg H, Scheller, Jürgen, Grötzinger, Joachim, Seegert, Dirk

Journal:

Expert Opinion on Therapeutic Targets

Year:

2007

Language:

english

File:

PDF, 377 KB

english, 2007

5

Lipid-Specific Membrane Activity of Human β-Defensin-3 †

Böhling, Arne, Hagge, Sven O., Roes, Stefanie, Podschun, Rainer, Sahly, Hany, Harder, Jürgen, Schröder, Jens-Michael, Grötzinger, Joachim, Seydel, Ulrich, Gutsmann, Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

6

Extinction of Cloudina and Namacalathus at the Precambrian-Cambrian boundary in Oman

Amthor, Joachim E., Grotzinger, John P., Schröder, Stefan, Bowring, Samuel A., Ramezani, Jahandar, Martin, Mark W., Matter, Albert

Journal:

Year:

2003

Language:

english

File:

PDF, 1.17 MB

english, 2003

7

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

Lokau, Juliane, Nitz, Rebecca, Agthe, Maria, Monhasery, Niloufar, Aparicio-Siegmund, Samadhi, Schumacher, Neele, Wolf, Janina, Möller-Hackbarth, Katja, Waetzig, Georg H., Grötzinger, Joachim, Müller-N

Journal:

Year:

2016

Language:

english

File:

PDF, 3.87 MB

english, 2016

8

ADAM10 sheddase activation is controlled by cell membrane asymmetry

Bleibaum, Florian, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina

Journal:

Journal of Molecular Cell Biology

Year:

2019

Language:

english

File:

PDF, 1.99 MB

english, 2019

9

The family of the IL-6-Type cytokines: Specificity and promiscuity of the receptor complexes

Joachim Grotzinger, Günther Kurapkat, Axel Wollmer, Michael Kalai, Stefan Rose-John

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1997

Language:

english

File:

PDF, 510 KB

english, 1997

10

Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones

Hans Iding, Thomas Dünnwald, Lasse Greiner, Andreas Liese, Michael Müller, Petra Siegert, Joachim Grötzinger, Ayhan S. Demir, Martina Pohl

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 276 KB

english, 2000

11

Alteration of the Substrate Specificity of Benzoylformate Decarboxylase from Pseudomonas putida by Directed Evolution

Bettina Lingen, Doris Kolter-Jung, Pascal Dünkelmann, Ralf Feldmann, Joachim Grötzinger, Martina Pohl, Michael Müller

Journal:

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

12

Functional characterization of GNAS mutations found in patients with pseudohypoparathyroidism type Ic defines a new subgroup of pseudohypoparathyroidism affecting selectively Gsα-receptor interaction

Susanne Thiele, Luisa de Sanctis, Ralf Werner, Joachim Grötzinger, Cumhur Aydin, Harald Jüppner, Murat Bastepe, Olaf Hiort

Journal:

Year:

2011

Language:

english

File:

PDF, 260 KB

english, 2011

13

Calculation of the circular dichroism spectrum of cyclo(l-tyr-l-tyr) based on a molecular dynamics simulation

Jörg Fleischhauer, Joachim Grötzinger, Bernd Kramer, Peter Krüger, Axel Wollmer, Robert W. Woody, Elke Zobel

Journal:

Biophysical Chemistry

Year:

1994

Language:

english

File:

PDF, 978 KB

english, 1994

14

Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis

Ingrid Tacken, Heike Dahmen, Olivier Boisteau, Stéphane Minvielle, Yannick Jacques, Joachim Grötzinger, Andrea Küster, Ursula Horsten, Chrystel Blanc, Felix A. Montero-Julian, Peter C. Heinrich, Gerha

Journal:

Year:

1999

Language:

english

File:

PDF, 856 KB

english, 1999

15

Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells

Susanne H. Hoischen, Petra Vollmer, Pia März, Suat Özbek, Katharina S. Götze, Christian Peschel, Thomas Jostock, Till Geib, Jürgen Müllberg, Sabine Mechtersheimer, Martina Fischer, Joachim Grötzinger,

Journal:

Year:

2000

Language:

english

File:

PDF, 688 KB

english, 2000

16

Solution structure of a mini IGF-1

Elke De Wolf, Raj Gill, Stella Geddes, Jim Pitts, Axel Wollmer, Joachim Grötzinger

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 7.50 MB

english, 1996

17

Updating interleukin-6 classic- and trans-signaling

Jürgen Scheller, Joachim Grötzinger, Stefan Rose-John

Journal:

Signal Transduction

Year:

2006

Language:

english

File:

PDF, 2.73 MB

english, 2006

18

The residue E351 is essential for the activity of human 21-hydroxylase: evidence from a naturally occurring novel point mutation compared with artificial mutants generated by single amino acid substitutions

Nils Krone, Felix G. Riepe, Joachim Grötzinger, Carl-Joachim Partsch, Jürgen Brämswig, Wolfgang G. Sippell

Journal:

Journal of Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

19

Enantiomeric resolution of amino acid derivatives on chiral stationary phases by high-performance liquid chromatography

Götz Krüger, Joachim Grötzinger, Heinz Berndt

Journal:

Journal of Chromatography A

Year:

1987

Language:

english

File:

PDF, 564 KB

english, 1987

20

Mutagenesis of catalytically important residues of cupin type phosphoglucose isomerase from Archaeoglobus fulgidus

Thomas Hansen, Bettina Schlichting, Joachim Grötzinger, Michael K. Swan, Christopher Davies, Peter Schönheit

Journal:

Year:

2005

Language:

english

File:

PDF, 468 KB

english, 2005

21

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

Fischer, Martina, Goldschmitt, Jutta, Peschel, Christian, Brakenhoff, Just P. G., Kallen, Karl-Josef, Wollmer, Axel, Grötzinger, Joachim, Rose-John, Stefan

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 505 KB

1997

22

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

Yu, Mei, Schreek, Sabine, Cerni, Christa, Schamberger, Chantal, Lesniewicz, Krzysztof, Poreba, Elzbieta, Vervoorts, Jörg, Walsemann, Gesa, Grötzinger, Joachim, Kremmer, Elisabeth

Journal:

Year:

2005

Language:

english

File:

PDF, 1.54 MB

english, 2005

23

Letter to the Editor:1H,15N and13C Backbone Assignment of the Carboxyl Terminal Domain of the Cytokine Binding Module of the Interleukin-6 Receptor

Andreas Schwantner, Andrew J. Dingley, Suat Özbek, Oliver Hecht, Stefan Rose-John, Joachim Grötzinger

Journal:

Journal of Biomolecular NMR

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

24

A bioinformatical approach suggests the function of the autoimmune hepatitis target antigen soluble liver antigen/liver pancreas

Thomas Kernebeck, Ansgar W. Lohse, Joachim Grötzinger

Journal:

Year:

2001

Language:

english

File:

PDF, 316 KB

english, 2001

25

The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region

Thomas Kernebeck, Stefan Pflanz, Peter C. Heinrich, Axel Wollmer, Joachim Grötzinger, Gerhard Müller-Newen, Günther Kurapkat, Stephan Grzesiek, Ruud M. Scheek, Klaas Dijkstra

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 2.19 MB

english, 1999

26

The solution structure of a superpotent b-chain-shortened single-replacement insulin analogue

Günther Kurapkat, Michael Siedentop, Hans-Gregor Gattner, Michael Hagelstein, Dietrich Brandenburg, Joachim Grötzinger, Axel Wollmer

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 1.20 MB

english, 1999

27

Viral Interleukin-6: Structure, pathophysiology and strategies of neutralization

Jan Suthaus, Nina Adam, Joachim Grötzinger, Jürgen Scheller, Stefan Rose-John

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

28

The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution

Inken Lorenzen, Weifeng Shang, Markus Perbandt, Maxim V. Petoukhov, Dmitri I. Svergun, Georg H. Waetzig, Stefan Rose-John, Rolf Hilgenfeld, Joachim Grötzinger

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

29

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II

Inken Lorenzen, Juliane Lokau, Stefan Düsterhöft, Ahmad Trad, Christoph Garbers, Jürgen Scheller, Stefan Rose-John, Joachim Grötzinger

Journal:

Year:

2012

Language:

english

File:

PDF, 943 KB

english, 2012

30

Development of sandwich ELISA for detection and quantification of human and murine a disintegrin and metalloproteinase17

Ahmad Trad, Nina Hedemann, Mohammad Shomali, Verena Pawlak, Joachim Grötzinger, Inken Lorenzen

Journal:

Journal of Immunological Methods

Year:

2011

Language:

english

File:

PDF, 533 KB

english, 2011

31

Ancient weapons: the three-dimensional structure of amoebapore A

Matthias Leippe, Heike Bruhn, Oliver Hecht, Joachim Grötzinger

Journal:

Trends in Parasitology

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

32

Antimicrobial activity of bovine psoriasin

Petra Regenhard, Matthias Leippe, Sabine Schubert, Rainer Podschun, Ernst Kalm, Joachim Grötzinger, Christian Looft

Journal:

Veterinary Microbiology

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

33

Monoclonal antibodies against the human interleukin-11 receptor alpha-chain (IL-11Rα) and their use in studies of human mononuclear cells

Chrystel Blanc, Patricia Vusio, Karin Schleinkofer, Olivier Boisteau, Stefan Pflanz, Stéphane Minvielle, Joachim Grötzinger, Gerhard Müller-Newen, Peter C Heinrich, Yannick Jacques, Félix A Montero-Ju

Journal:

Journal of Immunological Methods

Year:

2000

Language:

english

File:

PDF, 1.37 MB

english, 2000

34

Molecular mechanisms of cytokine receptor activation

Joachim Grötzinger

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

35

New perspectives on the design of cytokines and growth factors

Karl-Josef Kallen, Joachim Grötzinger, Stefan Rose-John

Journal:

Trends in Biotechnology

Year:

2000

Language:

english

File:

PDF, 488 KB

english, 2000

36

Antimicrobial peptides and proteins of the horse - insights into a well-armed organism

Oliver Bruhn, Joachim Grötzinger, Ingolf Cascorbi, Sascha Jung

Journal:

Veterinary Research

Year:

2011

Language:

english

File:

PDF, 2.30 MB

english, 2011

37

Cyclic disulfide analogues of the complement component C3a Synthesis and conformational investigations

MARTINA POHLS, DOROTHEE AMBROSIUS, JOACHIM GRÖTZINGER, TITUS KRETZSCHMAR, DEREK SAUNDERS, AXEL WOLLMER, DIETRICH BRANDENBURG, DIETER BITTER-SUERMANN, HARTWIG HÖCKER

Journal:

Chemical Biology & Drug Design

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

38

Determination of the three-dimensional solution structure of the histidine-containing phosphocarrier protein HPr from Escherichia coli using multidimensional NMR spectroscopy

Nico A. J. van NULAND, Joachim GRÖTZINGER, Klaas DIJKSTRA, Ruud M. SCHEEK, George T. ROBILLARD

Journal:

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

39

Reversible Dissociation and Unfolding of Pyruvate Decarboxylase from Zymomonas mobilis

Martina Pohl, Joachim Grötzinger, Axel Wollmer, Maria-Regina Kula

Journal:

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

40

Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor

Peter BUBECK, Joachim GRÖTZINGER, Monica WINKLER, Jörg KÖHL, Axel WOLLMER, Andreas KLOS, Wilfried BAUTSCH

Journal:

Year:

1994

Language:

english

File:

PDF, 1.29 MB

english, 1994

41

The Replacement of Trp392 by Alanine Influences the Decarboxylase/Carboligase Activity and Stability of Pyruvate Decarboxylase from Zymomonas mobilis

Heike Bruhn, Martina Pohl, Joachim Grötzinger, Maria-Regina Kula

Journal:

Year:

1995

Language:

english

File:

PDF, 530 KB

english, 1995

42

Site-Directed Mutagenesis of Conserved Charged Residues in the Helical Region of the Human C5a Receptor : Arg206 Determines High-Affinity Binding Sites of C5a Receptor

Ute Raffetseder, Detlef Röper, Laurence Mery, Claudia Gietz, Andreas Klos, Joachim Grötzinger, Axel Wollmer, François Boulay, Jörg Köhl, Wilfried Bautsch

Journal:

Year:

1996

Language:

english

File:

PDF, 1.36 MB

english, 1996

43

Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6 (IL-6)-Binding Sites of the Human IL-6 Receptor

Michael Kalai, Felix A. Montero-Julian, Joachim Grötzinger, Axel Wollmer, Danielle Morelle, Jean Brochier, Stefan Rose-John, Peter C. Heinrich, Hervé Brailly, Jean Content

Journal:

Year:

1996

Language:

english

File:

PDF, 1.25 MB

english, 1996

44

The Signal Transducer Gp130 — Bacterial Expression, Refolding and Properties of the Carboxy-Terminal Domain of the Cytokine-Binding Module

Gerhard Müller-Newen, Stefan Pflanz, Ulrich Hassiepen, Jürgen Stahl, Axel Wollmer, Peter C. Heinrich, Joachim Grötzinger

Journal:

Year:

1997

Language:

english

File:

PDF, 716 KB

english, 1997

45

Analysis of the Mechanism of Action of Anti-human Interleukin-6 and Anti-human Interleukin-6 Receptor-neutralising Monoclonal Antibodies

Michael Kalai, Fèlix A. Montero-julian, Just P. J. Brakenhoff, Véronique Fontaine, Lucas De Wit, Axel Wollmer, Hervé Brailly, Jean Content, Joachim Grötzinger

Journal:

Year:

1997

Language:

english

File:

PDF, 1.23 MB

english, 1997

46

The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex

Dorthe Aasland, Birgit Oppmann, Joachim Grötzinger, Stefan Rose-John, Karl-Josef Kallen

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 457 KB

english, 2002

47

Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130

Floris D. de Hon, Hanny Klaasse Bos, Saskia B. Ebeling, Joachim Grötzinger, Günther Kurapkat, Stefan Rose-John, Lucien A. Aarden, Just.P.J. Brakenhoff

Journal:

Year:

1995

Language:

english

File:

PDF, 477 KB

english, 1995

48

Use of immobilized synthetic peptides for the identification of contact sites between human interleukin-6 and its receptor

Oliver Weiergräber, Jens Schneider-Mergener, Joachim Grötzinger, Axel Wollmer, Andrea Küster, Markus Exner, Peter C. Heinrich

Journal:

Year:

1996

Language:

english

File:

PDF, 558 KB

english, 1996

49

Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130

Just P.J Brakenhoff, Hanny Klaasse Bos, Joachim Grötzinger, Stefan Rose-John, Lucien A Aarden

Journal:

Year:

1996

Language:

english

File:

PDF, 491 KB

english, 1996

50

Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain

Inken Lorenzen, Ahmad Trad, Joachim Grötzinger

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 838 KB

english, 2011

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